Sub-chronic
The Sub-chronic Study (Early Life-stage) exposes fertilized fish embryos through hatch, swim up, and for 4 to 8 weeks as juveniles, which includes key survival and growth endpoints. Typically, early fish life-stages are considered the most sensitive. Based on research conducted at Springborn and by others, this study design can accurately predict the effects from fish full life-cycle studies for approximately 80% of the chemicals tested.
Presently, the most commonly tested species include the freshwater species fathead minnow and rainbow trout, and the marine species sheepshead minnow. Springborn has considerable experience testing other species in early life-stage studies and can design custom studies to meet the needs of clients requiring specialized testing.
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