Dietary Toxicity Studies

Both acute and chronic effects of compounds can be evaluated through dietary studies. Substances that are poorly metabolized and that accumulate in some tissues, such as fat in the case of lipophilic substances, can pose a problems even though they are not acutely toxic. Even compounds with moderate ability to bioaccumulate may cause problems if toxic doses can be accumulated gradually over the course of several days. To provide required testing of such compounds Springborn Smithers Laboratories offers extensive avian dietary toxicology testing services at its CRC facility.

Springborn Smithers is perhaps the only large international company offering a full range of acute and chronic toxicity testing programs in birds, mammals, fish and invertebrate species. Our experienced and dedicated staff designs studies to respond to particular needs from laboratory to field. Our breadth of experience ranges from work with pen raised individuals to free ranging species. Dietary studies may be conducted with mallards, northern bobwhite quail, redwinged black birds, house finches, house sparrows or brown headed cowbirds. With years experience in the area of dietary toxicity testing Springborn Smithers has the experience and technical sophistication to meet FIFRA, TSCA, FDA, EU, OECD, J-MAFF, BBA, ASTM, ACOE and CERCLA requirements. Studies may also incorporate analytical chemistry and residue analysis. Our team of experienced avian toxicologists has performed field studies across the United Sates and Canada.